Compare current professional-society guidance on managing GLP-1 receptor agonists in the perioperative period, given the theoretical aspiration risk associated with delayed gastric emptying.
American Society of Anesthesiologists
MultisocietyMost patients can continue GLP-1 therapy through surgery; those at elevated risk follow a liquid diet for at least 24 hours or have the drug withheld case by case.
American Gastroenterological Association
MultisocietyAsymptomatic patients on standard fasting can proceed without holding; a liquid diet the day before is preferred over stopping the drug.
American Society for Gastrointestinal Endoscopy
For elective endoscopy, hold daily GLP-1 agonists at least 24 hours and weekly formulations at least 7 days, plus a liquid diet 24 hours before for all users.
Society for Perioperative Assessment and Quality Improvement
Continue GLP-1 therapy, paired with extended preoperative fasting of about 24 hours rather than routine cessation.
Society for Ambulatory Anesthesia
For ambulatory surgery in patients with diabetes, GLP-1 agonists are listed as hold on the day of surgery, echoing ASA's 2023 daily/weekly hold intervals.
American Society for Metabolic and Bariatric Surgery
MultisocietyCo-developed the 2024 multisociety guidance: no routine hold, with risk stratified by GI symptoms, dose, and dose-escalation status.